منابع مشابه
A bioinformatician's guide to metagenomics.
As random shotgun metagenomic projects proliferate and become the dominant source of publicly available sequence data, procedures for the best practices in their execution and analysis become increasingly important. Based on our experience at the Joint Genome Institute, we describe the chain of decisions accompanying a metagenomic project from the viewpoint of the bioinformatic analysis step by...
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BACKGROUND Metagenomic analyses have been widely used in the last decade to describe viral communities in various environments or to identify the etiology of human, animal, and plant pathologies. Here, we present a simple and standardized protocol that allows for the purification and sequencing of RNA viromes from complex biological samples with an important reduction of host DNA and RNA contam...
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We have models of commerce in a Web setting: business to business (B2B) and business to consumer (B2C). Now scientists commonly use Web based services to perform in-silico experiments. Thus we are prompted to ask the question "Are eScientists doing e-Business?". Do the infra-structure and models offered by eCommerce support the activities e-Scientists need to perform? In this position paper we ...
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Very few user analysis studies have been done in the bioinformatics domain. This paper presents the results of an exploratory user study as part of a domain and requirements analysis aimed at enhancing multidisciplinary collaboration. Contextual field observations, questionnaires and interviews with bioinformatics researchers of different levels of expertise and various backgrounds were perform...
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Whole genome shotgun sequencing (WGS) has been increasingly recognized as the most comprehensive and robust approach for metagenomics research. When compared with 16S-based metagenomics, it offers the advantage of identification of species level taxonomy and the estimation of metabolic pathway activities from human and environmental samples. Several large-scale metagenomic projects have been re...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 2008
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.00009-08